Sunday, September 19, 2010

Extrahepatic Manifestations

Complications that do not involve the liver develop in 1 to 2 percent of people with hepatitis C; the most common is cryoglobulinemia, which is marked by
  • skin rashes, such as purpura, vasculitis, or urticaria
  • joint and muscle aches
  • kidney disease
  • neuropathy
  • cryoglobulins, rheumatoid factor, and low-complement levels in serum
Other complications of chronic hepatitis C are
  • glomerulonephritis
  • porphyria cutanea tarda
Diseases that are less well documented to be related to hepatitis C are
  • seronegative arthritis
  • keratoconjunctivitis sicca (Sjögren's syndrome)
  • non-Hodgkin's type, B-cell lymphomas
  • fibromyalgia
  • lichen planus

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